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In this embodiment, the level of expression of the positive or negative regulatory protein (and, consequently each of the genes subject to their regulation) is dependent upon the level of revTet repressor protein in the cell and the concentration of tetracycline or tetracycline analog to which the prokaryotic host is exposed. The term "ester" includes compounds and moieties which contain a carbon or a heteroatom bound to an oxygen atom which is bonded to the carbon of a carbonyl group. He has been taking this drug for one month now and has noticed markable improvements.
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